MLB Same Game Parlay: Mariners vs Padres - April 16, 2026

By Barbara Fields

Apr 17th, 2026 2:56 PM EDT

Padres starting pitcher Walker Buehler

The Same Game Parlay has become a popular wager at online sportsbooks. MLB Same Game Parlays have especially taken off.

preprod.bookies.com has revealed the top MLB Same Game Parlay picks.

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MLB Mariners vs Padres Picks

San Diego enters the series finale with full sweep momentum, outscoring opponents 40-15 during their current win streak and covering 72.2% of their games (13-5-0 ATS) on the season. Seattle, meanwhile, is batting a staggering .158 on the road — the lowest mark in MLB — and slugging just .230 away from home, also last in baseball. The Mariners are 1-7 on the road this season, and Luis Castillo carries a 6.92 ERA and 1.77 WHIP through his 2026 starts. Petco Park's suppressive park factor of 0.92 adds further downward pressure on scoring, reinforcing the under as a natural companion to a Padres win.

Tonight's Best Bets

*Lines sourced from major US sportsbooks and are subject to change before tip-off.

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Pick 1: San Diego Padres moneyline (+102)

San Diego has gone 2-0 in this series, won every game during their streak by at least three runs, and is 13-5-0 ATS on the season, a 72.2% cover rate that leads the league. Seattle's road offense is historically bad: .158 batting average and .230 slugging on the road, both the lowest in MLB. Walker Buehler is coming off six shutout innings against Colorado, posting a .314 wOBA and .305 xwOBA through three starts, showing real improvement in command. With Mason Miller available for the ninth and a 29⅔-inning scoreless streak behind him, San Diego's path to a third straight win is well-supported by every relevant trend.

Pick 2: Walker Buehler over 4.5 strikeouts (-115)

Walker Buehler struck out four batters across six shutout innings in his most recent start, continuing to sharpen his command since joining San Diego. He has logged 11 strikeouts over three starts this season, averaging roughly 3.7 per outing, and faces a Seattle lineup that is batting .205 as a team. Buehler's Statcast hard-hit rate sits at just 33.3%, indicating hitters are not squaring him up consistently. Seattle's road lineup has produced anemic results; the Mariners rank among the worst road offenses in baseball, making Buehler's over 4.5 Ks an achievable target against a lineup that struggles to make consistent, quality contact.

Pick 3: Under 8.5 runs (-122)

Petco Park carries a park factor of 0.92, one of the more pitcher-friendly environments in the NL, naturally suppressing run totals. Seattle is averaging just 3.9 runs per game overall (T-24th in MLB), and their road production has been even worse, with their slugging sitting at .230 away from home - dead last in baseball. San Diego's pitching staff has allowed just 3.6 runs per game (T-5th in MLB), and Buehler's recent form, six scoreless innings in his last start, suggests he can keep this game in check deep into the middle frames. The combination of elite home pitching, a suppressive ballpark, and Seattle's dysfunctional road offense makes under 8.5 runs the most structurally sound leg of this parlay.

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Mariners vs Padres Same-Game Parlay

San Diego Padres moneyline + Walker Buehler over 4.5 strikeouts + Under 8.5 runs

Buehler commands the zone early, limiting Seattle's struggling road offense through five or six innings while keeping the Mariners off the board or to a single run. The Padres plate two to three runs against Castillo in the middle innings, leveraging their lineup's hot stretch, 40 runs scored during the win streak, without needing a high-scoring affair. Mason Miller closes out the ninth, extending his scoreless streak and locking in the sweep.

Injury Report

Seattle Mariners

San Diego Padres

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Mariners vs Padres Final Prediction

Walker Buehler builds on his best start as a Padre, keeping Seattle's anemic road offense quiet through six innings while the San Diego lineup does just enough against a struggling Castillo. The Padres complete the sweep at Petco Park, winning a low-scoring game that stays well under the total and fits every piece of this game script.

Predicted Score: San Diego Padres 4, Seattle Mariners 1

Game Details

*Lines sourced from major US sportsbooks and are subject to change before tip-off.

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